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In the example below, you can see that this sublingual B12, which can be taken daily, has 1000 mcg

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Claudin-2 (CLDN2) and claudin-15 (CLDN15) are the main pore forming claudins expressed in the gastrointestinal tract and both of these claudins form cation specific pores [25, 26], permitting the paracellular transport of sodium ions